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Fertility Specialist Dr Apurva Amarnath Explains All You Need To Know About Intrauterine Insemination (IUI)

Couples who wish to conceive but face fertility issues need not give up on their dreams. There are several fertility treatments and options to conceive. Intrauterine insemination is a fertility procedure that is typically quick and painless. But understandably, there are questions about this treatment. Would it hurt? Would there be a lot of cramping afterwards? Could something unexpectedly go awry? To answer these and other similar questions about Intrauterine Insemination (IUI), TC46 connected with Fertility Specialist Dr Apurva Amarnath Dr Apurva Satish Amarnath from Nova IVF Fertility, Bangalore. Here, he explains how IUI works, the risk factors involved, the success rate and the procedure.

1. What is Intrauterine Insemination (IUI)? What is the difference between IUI & IVF?

IUI is the process of insertion of processed sperm into the uterus, which helps healthy sperm get closer to the egg to aid fertilization. IVF would entail stimulation of ovaries to grow the follicles, following which an ovarian follicular aspiration is done and the harvested egg is fertilized in the lab with the sperm.

2. Who qualifies for this fertility treatment and when is it used?

The current indications of IUI are: – Unexplained infertility – Mild male factor – Ejaculator/erectile dysfunction – If donor sperm insemination is required – here intercourse is to be avoided i.e. HIV infection

3. How can an IUI cycle help to improve the chances of pregnancy? Is there a risk for twins or triplets with IUI?

The chances of natural conception per cycle vary between 6-8%. IUI helps in improving the pregnancy rate to 15-20% by increasing the proximity of the egg with the sperm. When combined with ovulation induction, there is a 10-12 % risk of multiple pregnancies.

4. What are the different treatment cycles of IUI and what do they include?

IUI is usually done in combination with ovulation induction. The various protocols used would be using medication(tablets), injections or a combination of the two, depending on the patient condition. This includes starting the medication on D2/3 of a cycle, follicular monitoring, triggering ovulation when the dominant follicle reached the appropriate size followed by the IUI

5. How long can you have hypothyroidism without knowing?

The procedure of IUI is simple. It entails: – Selection and counselling – Ovarian Stimulation – Monitoring of follicular growth and endometrial development – Timing of insemination is planned ~ 36 hours after the trigger injection – Sperm preparation – Insemination

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