Reason 1 It is thought that the female immune system is more robust & more reactive. Hence, women get autoimmune diseases in far greater numbers than men
Reason 2 It appears that hormones affect RA risks and flares. Estrogen and Progesterone levels frequently change due to menstruation, pregnancy, and even menopause.
Reason 3 Many women with RA who get pregnant experience fewer or no symptoms, only to find that they reappear after the baby is born.
Reason 4 Genetic risk factors could also lead to more prevalence of the disease in women. Genes specific to the X chromosome are among newly identified genes linked to RA.
Reason 5 Environmental factors like diet and smoking are shown to impact the prevalence of RA